Cisplatin electrolyte abnormalities

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August undefined, 2024

WebNov 1, 2024 · Special attention needs to be paid to electrolyte disturbances, which should be particularly considered when administering high doses of cisplatin [19]. The most common electrolyte disorder is ... WebNational Center for Biotechnology Information

Cisplatin induced arrhythmia; electrolyte imbalance or disturbance …

Web• Hypomagnesemia and Accompanying Electrolyte Abnormalities: Monitor during treatment and for at least 8 weeks following the completion. Replete electrolytes as necessary. (5.6) ... and Cisplatin . 5.6 Hypomagnesemia and Accompanying Electrolyte Abnormalities . 5.7 Increased Tumor Progression, Increased Mortality, or Lack ... WebJul 20, 2024 · Electrolyte abnormalities that converge on hypomagnesemia and serve as important diagnostic clues to its presence include … bing chinese translate

Epidemiologic Characteristics of Acute Kidney Injury During Cisplatin …

http://www.ejmanager.com/mnstemps/93/93-1446132625.pdf#:~:text=The%20most%20common%20electrolyte%20abnormality%20associated%20with%20cisplatin,the%20incidence%20of%20which%20varies%20significantly%20between%20studies. WebApr 12, 2024 · In cancer patients, electrolyte disorders are frequent due to tubular functional abnormalities related to chemotherapeutic drugs, the TLS and the impaired secretion of antidiuretic hormone ... As previously described, also the cisplatin can induce electrolyte imbalances. In this case, the standard approach to avoid cisplatin-induced ... cytomel headaches

Reference ID: 3851135 - Food and Drug Administration

Cisplatin Drugs BNF NICE

WebJul 28, 2024 · Electrolyte Abnormalities: This medication can affect the normal levels of electrolytes (potassium, magnesium, calcium, etc.) in your body. Your levels will be … WebHypomagnesemia occurred in 83% of patients receiving PORTRAZZA in combination with gemcitabine and cisplatin, and was severe in 20% of patients. Monitor patients for hypomagnesemia, hypocalcemia, and hypokalemia prior to each dose of PORTRAZZA during treatment and for at least 8 weeks following completion of PORTRAZZA. cytomel generic namesWebNational Center for Biotechnology Information cytomel half-life

"WebJan 3, 2024 · A variety of kidney diseases and electrolyte disorders can result from the drugs that are used to treat malignant disease, including conventional cytotoxic agents; molecularly targeted agents, which take advantage of molecular abnormalities that drive cancer progression; and immunotherapeutic agents. " - Cisplatin electrolyte abnormalities

Cisplatin electrolyte abnormalities

WebSep 15, 2024 · Cisplatin is administered parenterally and is available in 50 and 100 mg vials in generic forms and under the brand name Platinol. The recommended dose varies by indication, tumor type, patient age and body weight. Common side effects include nausea, vomiting, bone marrow suppression, electrolyte imbalance, neuropathy, ototoxicity and ... WebMay 18, 2024 · Compared with young patients, the incidences of cisplatin-induced nephrotoxicity and acute kidney injury (AKI) in elderly patients are significantly increased, …

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WebOct 19, 2024 · Severe electrolyte abnormalities (secondary exposure) included ≥ grade three hypophosphatemia, hypokalemia, or hypomagnesemia (National Cancer Institute Common Terminology Criteria for Adverse Events v4.0). CKD was albuminuria or decreased kidney function for age (KDIGO guidelines). WebSep 18, 2024 · NCBI Bookshelf

WebCisplatin can cause increased magnesium losses by the kidneys as well as generalized decrease in kidney function. Magnesium loses can be severe and persist despite discontinuation of cisplatin. Discontinuation of cisplatin is still recommended if signs of renal toxicity occur during therapy. Table Causes of Hypomagnesemia WebJul 28, 2024 · Electrolyte Abnormalities: This medication can affect the normal levels of electrolytes (potassium, magnesium, calcium, etc.) in your body. Your levels will be monitored using blood tests. If your levels become too low, your care team may prescribe specific electrolytes to be given by IV or taken by mouth.

WebOct 19, 2024 · In the literature, cisplatin-associated electrolyte abnormalities are poorly described, but hypomagnesemia occurs in 14–94% of children [3, 4, 36, 38, 39]. CNS … WebCisplatin for injection is a highly emetogenic antineoplastic agent; premedicate with anti-emetic agents; without antiemetic therapy, marked nausea and vomiting occur in almost all patients treated with cisplatin …

WebMay 1, 2024 · The most common diagnoses were central nervous system tumors (58 [36%]), neuroblastoma (43 [27%]), and osteosarcoma (33 [21%]). Acute kidney injury (by serum creatinine level increase) occurred in 48 of 159 patients (30%) at early cisplatin infusions and 23 of 143 patients (16%) at late cisplatin infusions.

WebJun 24, 2024 · The most common electrolyte abnormalities were hypomagnesemia (88.9%, Vancouver) and hypophosphatemia (24.2%, Mexico City). ... Since nephrotoxicity is commonly found in cisplatin-treated children, electrolyte abnormalities can also help in understanding a patient’s kidney function, especially in the early stage of cisplatin … bing chit chat featureWebSep 15, 2024 · Deafness after the initial dose of cisplatin (cisplatin injection) has been reported rarely. Ototoxic effects may be more severe in children receiving cisplatin … cytomel lowest doseWebmay drive unique electrolyte disorders in different malignancies. In the next sections, the clinical fea-tures, pathophysiology, and treatment of the most … cytomel in thailandWebElectrolyte disorders with platinum-based chemotherapy: mechanisms, manifestations and management Platinum chemotherapy, particularly cisplatin, is commonly associated with electrolyte imbalances, including hypomagnesemia, hypokalemia, … cytomel heartWebSep 27, 2024 · Nephrotoxicity: cisplatin for injection can cause severe renal toxicity, including acute renal failure. Severe renal toxicities are dose-related and cumulative. Ensure adequate hydration and monitor renal function and electrolytes. cytomel hypothyroidismWebSep 15, 2024 · Cisplatin's side effects primarily include nephrotoxicity, gastrointestinal toxicity, neurotoxicity and ototoxicity. Cardiotoxicity is generally not defined as a side … bing chinese pancakeWebDec 9, 2024 · Electrolyte disorders are very common conditions in cancer patients. They mainly concern changes in serum sodium, potassium, calcium, and magnesium levels. In most cases, these alterations are asymptomatic and therefore not always taken into consideration in clinical practice. cytomel how long to work