Hydroxymethylglutaryl coenzyme a synthase

Author: qzpm

August undefined, 2024

Webhydroxymethylglutaryl-CoA synthase, mitochondrial, 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial), 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial), HMG-CoA synthase, testicular tissue protein Li 88. GeneRIFs: Gene References Into Functions. Web12 apr. 2024 · The MVA pathway generates IPP through six major catalytic steps, using the following enzymes: acetyl-coenzyme A acetyltransferase (ACAT), 3-hydroxy-3-methyl-glutaryl coenzyme A synthase (HMGS), hydroxymethylglutaryl coenzyme A reductase (HMGR), MVK, phosphomevalonate kinase (PMK), and mevalonate diphosphate …

ENZYME - 2.3.3.10 hydroxymethylglutaryl-CoA synthase

Web13 nov. 2009 · 3-Hydroxy-3-methylglutaryl coenzyme A (CoA) synthase (HMGCS) catalyzes the condensation of acetyl-CoA and acetoacetyl-CoA into 3-hydroxy-3-methylglutaryl CoA. It is ubiquitous across the phylogenetic tree and is … Web21 okt. 2014 · Plant cell cultures as valuable tools for the production of specific metabolites can be greatly improved by the application of elicitors including cyclodextrins (CDs) for enhancing the yields of the desired plant compounds. Here the effects of 2,6-dimethyl-β-cyclodextrins (DIMEB) on the production of carotenoids and quinones from Artemisia … chariti stewart

Hydroxymethylglutaryl-CoA synthase SpringerLink

Webアズワンの【AXEL】84-3498-99 HMGCS1 (3-hydroxy-3-methylglutaryl Coenzyme A Synthase, Hydroxymethylglutaryl-CoA Synthase Cytoplasmic, HMG-CoA Synthase, HMGCS, MGC90332) (FITC) 200ul H6207-50-FITCのコーナーです。AXELは研究開発、医療介護、生産現場、食品衛生など幅広い分野に750万点以上の品揃えでお応えする商品 … WebHydroxymethylglutaryl-CoA Synthase. An enzyme that catalyzes the synthesis of hydroxymethylglutaryl-CoA from acetyl-CoA and acetoacetyl-CoA. This is a key … WebHydroxymethylglutaryl-CoA synthase, mitochondrial EC number EC:2.3.3.10 ( UniProtKB ENZYME Rhea) 3 publications Short names HMG-CoA synthase Alternative names 3-hydroxy-3-methylglutaryl coenzyme A synthase Gene names Name HMGCS2 Organism names Organism Homo sapiens (Human) Taxonomic identifier 9606 NCBI Taxonomic … harry bbq claxton ga

Hydroxymethylglutaryl Coenzyme A Synthase - an overview

Functional Diversity of Genes for the Biosynthesis of Paeoniflorin …

WebScienceDirect.com Science, health and medical journals, full text ... Web3-Hydroxy-3-methylglutaryl-coenzyme A synthase (HMGS) is an enzyme in mevalonate biosynthesis. In plants, investigations have focused on HMG CoA reductase (HMGR) … chariti themeWebHuman cytoplasmic 3-hydroxy-3-methylglutaryl coenzyme A synthase: expression, purification, and characterization of recombinant wild-type and Cys129 mutant enzymes. … harry b combs

"Web31 jan. 2024 · Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level Hydroxymethylglutaryl Coenzyme A Synthase 2, Mitochondrial (HMGCS2) were tested on 3 different plates, 8 replicates in each plate. CV(%) = SD/meanX100. Intra-Assay: CV. 10%. Inter-Assay: CV12% " - Hydroxymethylglutaryl coenzyme a synthase

Hydroxymethylglutaryl coenzyme a synthase

Hmgcs2 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 [Mus …

WebHydroxymethylglutaryl-coenzyme A synthase C-terminal InterPro annotation. BLAST Add. Sequence: Expand table. Sequence similarities. Belongs to the thiolase-like superfamily. HMG-CoA synthase family. automatic annotation. Family and domain databases. CDD. cd00827 init_cond_enzymes 1 hit; Gene3D. WebThere are at least two isoenzymes of 3-hydroxy-3-methylglutaryl (HMG)-CoA synthase (EC 4.1.3.5) located in the mitochondrial matrix and the cytoplasm of hepatocytes, respectively. The mitochondrial enzyme is necessary for the synthesis of ketone bodies, which are important fuels during fasting. We report a child with a deficiency of this isoenzyme.

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Web21 feb. 2024 · 15360 - Gene ResultHmgcs2 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 [ (house mouse)] Enables hydroxymethylglutaryl-CoA synthase activity. … WebR.J. Kazlauskas, U.T. Bornscheuer, in Comprehensive Chirality, 2012 7.22.1.1 Natural Functions of Catalytic Promiscuity. One reason why catalytic promiscuity exists is that it is an essential part of multistep enzymatic reactions. Two examples are thiolase and the related HMG-CoA synthase (3-hydroxy-3-methyl-glutaryl coenzyme A synthase) …

WebA cDNA for the human cytoplasmic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase (EC 4.1.3.5) was subcloned and expressed from a T7-based vector in Escherichia coli. The over-produced enzyme was purified using a three-step protocol that generated 20 to 30 mg protein/liter cell culture. WebMammalian mitochondrial HMG-CoA synthase performs no known role in isoprenoid biogenesis. Intramitochondrial HMG-CoA serves instead as a precursor of the ketone …

WebThe structure of this beta-lactone, termed L-659,699, is (E,E)-11-[3-(hydroxy-methyl)-4-oxo-2-oxytanyl]-3,5,7-trimethyl-2,4 - undecadienenoic acid. A partially purified preparation of cytoplasmic HMG-CoA synthase from rat liver was inhibited by … Web3 mrt. 2010 · hydroxymethylglutaryl coenzyme A-condensing enzyme Class Transferases; Acyltransferases; Acyl groups converted into alkyl groups on transfer BRITE hierarchy Sysname acetyl-CoA:acetoacetyl-CoA C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming) Reaction (IUBMB)

Web3 mrt. 2010 · (S)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating) 3-hydroxy-3-methylglutaryl CoA synthetase 3-hydroxy-3-methylglutaryl coenzyme A synthase 3 ...

Web8 jan. 2024 · Predicted to enable several functions, including hydroxymethylglutaryl-CoA synthase activity; organic acid binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including acetyl-CoA metabolic process; cellular response to low-density lipoprotein particle stimulus; and farnesyl diphosphate … charitin wikiWebA cDNA for the human cytoplasmic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase (EC 4.1.3.5) was subcloned and expressed from a T7-based vector in … harry bbq menuWebA partially purified preparation of cytoplasmic HMG-CoA synthase from rat liver was inhibited by L-659,699 with an IC50 of 0.12 microM. The enzyme HMG-CoA reductase, … charitin goyco alexandraWebアズワンの【AXEL】84-3498-99 HMGCS1 (3-hydroxy-3-methylglutaryl Coenzyme A Synthase, Hydroxymethylglutaryl-CoA Synthase Cytoplasmic, HMG-CoA Synthase, … harry b cunninghamβ-Hydroxy β-methylglutaryl-CoA (HMG-CoA), also known as 3-hydroxy-3-methylglutaryl coenzyme A, is an intermediate in the mevalonate and ketogenesis pathways. It is formed from acetyl CoA and acetoacetyl CoA by HMG-CoA synthase. The research of Minor J. Coon and … Meer weergeven Mevalonate synthesis begins with the beta-ketothiolase-catalyzed Claisen condensation of two molecules of acetyl-CoA to produce acetoacetyl CoA. The following reaction involves the joining of acetyl-CoA Meer weergeven • Steroidogenic enzyme Meer weergeven HMG-CoA lyase breaks it into acetyl CoA and acetoacetate. Meer weergeven charititsWeb8 jan. 2024 · Summary. Predicted to enable several functions, including hydroxymethylglutaryl-CoA synthase activity; organic acid binding activity; and protein … harry bcWeb3-Hydroxy-3-Methylglutaryl-Coenzyme A is an intermediate for the synthesis of mevalonic acid, ketone bodies and cholesterol and a metabolic product for … charit khatri