Impact of mirna in atherosclerosis

Author: wufe

August undefined, 2024

Witryna19 lut 2016 · Over the past decade, microRNAs (miRNAs) have emerged as evolutionarily conserved, noncoding small RNAs that serve as important regulators …

Impact of miRNA in Atherosclerosis Arteriosclerosis, Thrombosis, …

Witryna27 lip 2024 · These findings imply that miR-142-5p may plays a role in the development of atherosclerosis. Next, we tested the effect of miR-142-5p on the 3′-UTR of ABCA1 using luciferase reporter constructs and demonstrated that miR-142-5p dose-dependently reduced mouse and human ABCA1 3′-UTR activities (Figure S11A and … Witryna1 wrz 2014 · Atherosclerosis is a chronic, inflammatory disease of the arterial wall that underlies many of the common causes of cardiovascular morbidity and mortality, including myocardial infarction (MI), and cerebrovascular and peripheral vascular disease. Early pathological descriptions viewed atherosclerosis as an end-stage … flip hinge

Targeted Suppression of miRNA-33 Using pHLIP Improves …

WitrynaHere, we aimed to screen the atherosclerosis-associated miRNAs and preliminarily investigate the potential regulatory mechanism of... Endothelial Cells, Atherosclerosis and Mesenchymal Cells ... WitrynaAtherosclerosis is a condition caused by lipid-induced inflammation of the vessel wall orchestrated by a complex interplay of various cell types, such as endothelial cells, smooth muscle cells, and macrophages. ... we outline the effects of miRNA-145, -126, and -155 in atherosclerosis in vivo. Downregulation of miR-145, which controls ... WitrynaAtherosclerosis and lipid biology. Adenylate cyclase type 9 antagonizes cAMP accumulation and regulates endothelial signalling involved in atheroprotection. ... Regulation and impact of cardiac lymphangiogenesis in pressure-overload-induced heart failure. Coraline Heron, Anais Dumesnil, Mahmoud Houssari, ... greatest catholic saints of all time

miRNA Regulome in Different Atherosclerosis Phenotypes

Gut Microbially Produced Indole-3-Propionic Acid Inhibits ...

Witryna22 sie 2024 · MicroRNA regulation of atherosclerosis. Circ Res. 2016; 118:703–720. doi: 10.1161/CIRCRESAHA.115.306300 Link Google Scholar; 118. Eken SM, Jin H, Chernogubova E et al.. MicroRNA-210 enhances fibrous cap stability in advanced atherosclerotic lesions. Circ Res. 2024; 120:633–644. doi: … Witryna22 lip 2024 · The authors hypothesized that ACP5, as a direct target of lncRNA-H19, causes atherosclerosis by affecting cellular proliferation and apoptosis (Huang et al. 2024). Many studies have reported that lncRNA-H19 functions as a ceRNA to sponge its target miRNAs such as microRNA let-7 (Hsu et al. 2014; Sun et al. 2024b; Cao et al. … flip hole whiteWitryna3 sty 2024 · Introduction: Atherosclerosis is a chronic disease characterized by the inflammatory process and lipid depositions. We previously reported that microRNA-216a (miR-216a) can accelerate the progression of atherosclerosis by promoting the polarization of M1 pro-inflammatory phenotype. Ginsenoside Rb2 (Rb2), the major … flip hitch ball

"Witryna1 wrz 2024 · Europe PMC is an archive of life sciences journal literature. " - Impact of mirna in atherosclerosis

Impact of mirna in atherosclerosis

A meta-analysis of the relationship between circulating microRNA …

Witryna13 kwi 2024 · Liu YL. Effect of microRNA-155 on immune inflammatory response in atherosclerosis [Master]: Tianjin Medical University; 2024. 23. Nazari-Jahantigh M, … Witryna18 maj 2024 · To determine the influence of advanced atherosclerosis on the levels of miRNA expression in coronary plaques, we performed initially a miRNA profile using …

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WitrynaDownload scientific diagram The enriched GO terms of twenty-five overlapped genes in atherosclerosis. from publication: Adipose-derived mesenchymal stem cells-derived … WitrynaAtherosclerosis is closely related to vascular dysfunction and hypertension. Ojeoksan (OJS), originally recorded in an ancient Korean medicinal book named “Donguibogam”, is a well-known, blended herbal formula. This study was carried out to investigate the beneficial effects of OJS on atherosclerosis in vitro and in vivo. Western-diet-fed …

Witryna1 wrz 2024 · Request PDF On Sep 1, 2024, Yao Lu and others published Impact of miRNA in Atherosclerosis Find, read and cite all the research you need on … Witryna19 sie 2024 · Atherosclerosis remains the leading cause of a broad spectrum of deadliest cardiovascular diseases. MicroRNA‐33 is a new therapeutic target for atherosclerosis due to its diverse functions. However, it remains a great challenge in clinical translation of nucleic acid‐based microRNA‐targeting therapeutics. …

Witryna18 gru 2013 · By using a technology called "locked nucleic acids," Jo and his colleagues tested the effects of blocking miR-712 in the body. When given to mice in the rapid atherosclerosis model, the anti-miR-712 drug inhibited the development of arterial blockages. Without the drug, plaques blocked an average of 80 percent of the … Witryna20 mar 2024 · Background: Atherosclerosis (AS) is a major risk factor for cardiovascular disease. microRNAs play a key role in gene regulation in the formation and …

Witryna21 kwi 2024 · MicroRNA dysregulation occurs in many human diseases, including atherosclerosis. Here, we examined the serum expression and clinical significance …

Witryna20 mar 2024 · Background: Atherosclerosis (AS) is a major risk factor for cardiovascular disease. microRNAs play a key role in gene regulation in the formation and development of atherosclerotic plaques.Herein, the role and target gene of miR-185 in AS were explored. Materials and methods: Cell viability, migration and invasion were examined … flip hmtl5WitrynaThe let-7 miRNA family plays a key role in modulating inflammatory responses. Vascular smooth muscle cell (SMC) proliferation and endothelial cell (EC) dysfunction are critical in the pathogenesis of atherosclerosis, including in the setting of diabetes. Here we report that let-7 levels are decrease … flip hitchWitrynaThis review highlights the impact of microRNA-33-mediated regulation in the major cardiometabolic risk factors of atherosclerosis including lipid metabolism (HDL biogenesis and cholesterol homeostasis, fatty acid, phospholipid and triglyceride, bile acids metabolism), inflammatory response, insulin signaling and glucose/energy … flip hole tool orientation solidworksWitrynaBACKGROUND: Oxidative stress is a new risk factor for atherosclerosis. Increased oxidative stress in hemodialysis (HD) patients may arise from uremia-associated metabolic/humoral abnormalities and bi flip his lidWitryna15 gru 2024 · The specific mechanism of miRNA contributing to atherosclerosis varies depending on the cell types (Hosen et al., 2024). Leeper et al. summarized the key role miRNA played in VSMCs in atherosclerosis, and they suggested that miRNA could potentially be a biomarker when diagnosing and treating this disease (Leeper and … greatest cellistsWitrynaInhibition of miR-33 results in increased cholesterol efflux and HDL-cholesterol levels in mice. In this study we examined the effect of miR-33 inhibition in a mouse model of atherosclerosis and observed significant reduction in atherosclerotic plaque size. At the end of the study, gene expression in macrophages from the atherosclerotic plaques … greatest ccr songsWitryna13 gru 2024 · Circulating MiRNAs as Potential Clinical Biomarkers for Atherosclerosis and CVD. Extensive research has revealed that miRNAs are extremely stable and … flip holiday diaper cover